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Canadian Journal of Anesthesia, Vol 31, S82-S83, Copyright © 1984 by Canadian Anesthesiologists' Society

Abstracts: The Effects of Subarachnoid 2-Chloroprocaine-CE on the Spinal Cord

R. KOZODY 1, D. DUVAL 1, D. BIEHL 1, and L. CRUICKSHANK 1

1 Department of Anaesthesia, University of Manitoba, Winnipeg, Manitoba

A significant increase in lumbosacral SCBF was demonstrated at 40 min following intrathecal chloroprocaine. The hyperaemic response seen with 2-chloroprocaine-CE is similar to that occurring following subarachnoid tetracainc (20 mg) administration in dogs.2 Our results indicate that 2-chloroprocaine-CE does not induce acute spinal cord vasospasm in dogs following subarachnoid injection. Possible mechanisms responsible for prolonged neurological deficits following subarachnoid 2-chloroprocaine-CE will be discussed.






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Copyright © 1984 by the Canadian Anesthesiologists' Society.