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Canadian Journal of Anesthesia, Vol 32, 231-234, Copyright © 1985 by Canadian Anesthesiologists' Society

Rectal Methohexitone Induction in Pediatric Outpatients: Physostigmine does not Enhance Recovery

RAAFAT S. HANNALLAH MD1, MICHAEL D. ABRAMOWITZ MD1, WILLIS A. McGILL MD1, and BURTON S. EPSTEIN MD1

1 Department of Anesthesiology, Child Health and Development, Children's Hospital National Medical Center and George Washington University, Washington, D.C.

Address correspondence to: Dr. R. Hannallah, 111 Michigan Avenue, N.W., Washington, D.C. 20010.

Rectal methohexitone (25 mg·kg-1) was used to induce anaesthesia in 15 unpremedicated children scheduled to undergo bilateral myringotomies as outpatients. Induction time ranged from 4 to 11 minutes. In the recovery room, all children received a slow intravenous injection of physostigmine (60 µg·kg-1), or saline in a double blind randomized fashion. The use of physostigmine did not significantly decrease the recovery room stay as compared to placebo (34 vs. 43 minutes). Vomiting and soiling were two side-effects associated with the use of hysostigmine.

Key Words: ANAESTHESIA: outpatient, pediatric, induction • ANAESTHETICS: rectal, methohexitone • ANTAGONISTS: physostigmine






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Copyright © 1985 by the Canadian Anesthesiologists' Society.