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Canadian Journal of Anesthesia, Vol 33, 209-212, Copyright © 1986 by Canadian Anesthesiologists' Society

Clinical Reports: Prolonged Neuromuscular Blockade with Atracurium

MARINA D. BIZZARRI-SCHMID MD1 and SUKUMAR P. DESAI MD1

1 Department of Anaesthesia, Harvard Medical School, Brigham and Women's Hospital, Boston, MA 02115

where communications should be addressed to Dr. Desai.

During general anaesthesia with oxygen, nitrous oxide and enflurane, a 29-year-old woman received a total of 105 mg (1.78 mg·kg-1.) of atracurium over a 2.5 hour period. The neuromuscular blockade could not be completely reversed with neostigmine and mechanical ventilatory support was necessary for three hours postoperatively. The patient received succinylcholine without unusual sequelae before and after this episode. This is the first report of a patient who exhibited prolonged weakness after receiving atracurium.

Key Words: NEUROMUSCULAR RELAXANTS: atracurium • NEUROMUSCULAR JUNCTION: blockade






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Copyright © 1986 by the Canadian Anesthesiologists' Society.