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Canadian Journal of Anesthesia, Vol 33, 213-215, Copyright © 1986 by Canadian Anesthesiologists' Society

Cyanosis of the Hands Following the use of Alphaprodine in Dental Anaesthesia

H. D. FULLER MB BS FRCPC1

1 Brantford General Hospital, Brantford, Ontario

Address correspondence to: Dr. H.D. Fuller, Department of Medicine, St Joseph's Hospital, 50 Charlton Ave. East, Hamilton, Ontario, L8N 4A6.

A case is presented of asymptomatic cyanosis of the hands, seen four hours after dental surgery under intravenous, local and inhalational anaesthesia. Alphaprodine hydrochloride, a synthetic opiate and one of the agents used, may produce dilatation of the venous bed with passive venous pooling. Such a mechanism is thought to have occurred in this case, manifesting as cyanosis. A weakly positive intradermal skin test to alphaprodine suggests immediate type hyper sensitivity as a possible underlying cause.

Key Words: ANALGESICS: alphaprodine • COMPLICATIONS: cyanosis, hypersensitivity






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Copyright © 1986 by the Canadian Anesthesiologists' Society.