CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by FRIESEN, R. M.
Right arrow Articles by CANNON, J. E.
Right arrow Search for Related Content
PubMed
Right arrow Articles by FRIESEN, R. M.
Right arrow Articles by CANNON, J. E.

Canadian Journal of Anesthesia, Vol 33, 719-722, Copyright © 1986 by Canadian Anesthesiologists' Society

Fentanyl Oxygen Anaesthesia For Abdominal Aortic Surgery

ROBERT M. FRIESEN MD FRCPC1, IAN R. THOMSON MD FRCPC1, ROBERT J. HUDSON MD FRCPC1, MORLEY ROSENBLOOM BSC (Hon)1, CHARLES L. PUTNINS MD FRCPC1, and JOHN E. CANNON MD FRCPC1

1 Department of Anaesthesia, University of Manitoba, Winnipeg, Manitoba

Address correspondence to: Dr. R.M. Friesen, Department of Anaesthesia, St. Boniface General Hospital, 409 Tache Avenue, Winnipeg, Manitoba, R2H 2A6.

Patients who present for abdominal aortic surgery often have significant atherosclerotic disease which may involve the coronary arteries. Haemodynamic responses occurring during fentanyl (100 µ·kg-1) oxygen anaesthesia for abdominal aortic surgery were studied in 16 patients. Anaesthesia was induced with fentanyl 100 µ·kg-1 with no supplemental doses and metocurine-pancuronium mixture (4:1). In 13 of 16 patients hyperdynamic circulatory responses to surgical stimuli required treatment prior to aortic cross-clamping. Interventions instituted were sodium nitroprusside or nitroglycerin (n = 13), propranolol (n = 4), and diazepam (n = 4). The serum fentanyl concentration at time of response to surgical stimulus was 18.5 ± 5.6 ng·-1 (range 7-27 ng·ml-1; time from induction 71 ± 49 min, n = 9). Eleven of the 16 patients required treatment for postoperative hypertension. Five of the 16 patients developed myocardial ischaemia, defined as ST segment depression greater than 0.1mV, at some time during the operative procedure. Unsupplemented fentanyl anaesthesia (100 µ·kg-1) was unable to maintain a hypodynamic circulation in patients having abdominal aortic operations.

Key Words: ANAESTHETICS, INTRAVENOUS: fentanyl • SURGERY: vascular, aortic






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1986 by the Canadian Anesthesiologists' Society.