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Canadian Journal of Anesthesia, Vol 34, 509-511, Copyright © 1987 by Canadian Anesthesiologists' Society

ARTICLES

Effect of pre-eclampsia on plasma cholinesterase activity

JR Kambam, S Mouton, S Entman, BV Sastry and BE Smith
Vanderbilt University Medical Center, Department of Anesthesiology, Nashville, Tennessee.

Plasma cholinesterase (PCHE) activity was determined using a colorimetric method in 11 healthy non-pregnant women, 11 healthy pregnant women at term, and 11 pre-eclamptic pregnant women at term. The mean plasma cholinesterase activities for healthy non-pregnant women, healthy pregnant women and pre-eclamptic pregnant women were 438 +/- 81,257 +/- 25 and 173 +/- 18 units . ml-1, respectively. Our data suggest that there is a significant reduction in plasma cholinesterase activity in preeclamptic pregnant women when compared to healthy non-pregnant (p less than 0.001) and healthy pregnant women (p less than 0.001).




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Copyright © 1987 by the Canadian Anesthesiologists' Society.