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Canadian Journal of Anesthesia, Vol 36, 637-640, Copyright © 1989 by Canadian Anesthesiologists' Society

ARTICLES

Visual evoked potentials during thiopentone-fentanyl-nitrous oxide anaesthesia in humans

OZ Chi, S Ryterband and C Field
Department of Anesthesia, University of Medicine and Dentistry, New Jersey-Robert Wood Johnson Medical School, Robert Wood Johnson University Hospital, New Brunswick 08903-0019.

Visual evoked potentials (VEP) during thiopentone-fentanyl-nitrous oxide anaesthesia were studied in 15 healthy patients undergoing non-neurosurgical procedures. The VEP was recorded before and at 1 and 2 min after induction of anaesthesia with 5-6 mg.kg-1 of thiopentone. After recording the 1 and 2 min VEPs, anaesthesia was maintained with a fentanyl-nitrous oxide-oxygen combination, and further recordings were made at 5, 10, 15 and 20 min after induction. The 1 and 2 min VEPs showed a marked decrease in the amplitudes. Latencies were increased. The amplitudes gradually returned to the control level at 15 min, while the latencies remained increased throughout the study period. In conclusion, thiopentone should be avoided during the critical period of VEP recording. Once it is given, at least 15 min should elapse before an appropriate interpretation of the VEP can be made. Thiopentone-fentanyl-nitrous oxide anaesthesia slightly increases the latencies of the VEP. These effects should be considered in the interpretation of the VEP when thiopentone-fentanyl-nitrous oxide anaesthesia is used.


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G. Iohom, I. Collins, D. Murphy, I. Awad, G. O'Connor, N. McCarthy, and G. Shorten
Postoperative changes in visual evoked potentials and cognitive function tests following sevoflurane anaesthesia
Br. J. Anaesth., December 1, 2001; 87(6): 855 - 859.
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Copyright © 1989 by the Canadian Anesthesiologists' Society.