| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Canadian Journal of Anesthesia, Vol 37, 747-754, Copyright © 1990 by Canadian Anesthesiologists' Society
ARTICLES |
KA Brown, B Bissonnette and B McIntyre
Department of Anaesthesia, Hospital for Sick Children, University of Toronto, Ontario.
A morbidity and mortality review documented a high occurrence of hyperkalaemia in cardiac arrests associated with rapid blood transfusion, which resulted in further study. In order to stimulate events during rapid blood transfusion and cardiac arrest, the central circulation was modeled as a linear one compartment, and used to stimulate a child who suffered a hypovolaemic cardiac arrest and was resuscitated with rapid blood transfusion (RBT). The simulation suggested that the combination of RBT and a low cardiac output state could be associated with hyperkalaemia, if the potassium concentration in the plasma fraction of the transfused blood was greater than or equal to 10 mmol.L-1. In an associated clinical study the plasma potassium concentration during cardiac arrest was documented from a retrospective review of 138 cardiac arrests in a paediatric population. Patients were divided into two groups. The RBT-group received a rapid blood transfusion during resuscitation. The non-RBT group did not receive blood during resuscitation. During cardiac arrest the plasma [K] in the non-RBT group was 5.63 +/- 2.39 mmol.L-1 compared with 8.23 +/- 1.99 mmol.L-1 in the RBT-group (P less than 0.05). The hyperkalaemia during cardiac arrest in the RBT-group could be explained as a consequence of RBT to a hypovolaemic child with a low cardiac output.
This article has been cited by other articles:
 |
|
 |
|
  H. M. Smith, S. J. Farrow SRNA, J. D. Ackerman, J. R. Stubbs, and J. Sprung Cardiac Arrests Associated with Hyperkalemia During Red Blood Cell Transfusion: A Case Series Anesth. Analg., April 1, 2008; 106(4): 1062 - 1069. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. M. Bhananker, C. Ramamoorthy, J. M. Geiduschek, K. L. Posner, K. B. Domino, C. M. Haberkern, J. S. Campos, and J. P. Morray Anesthesia-Related Cardiac Arrest in Children: Update from the Pediatric Perioperative Cardiac Arrest Registry Anesth. Analg., August 1, 2007; 105(2): 344 - 350. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. M. Perkins, M. C. Aboudara, K. C. Abbott, and J. B. Holcomb Resuscitative Hyperkalemia in Noncrush Trauma: A Prospective, Observational Study Clin. J. Am. Soc. Nephrol., March 1, 2007; 2(2): 313 - 319. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Guay, P. de Moerloose, and D. Lasne Minimizing perioperative blood loss and transfusions in children: [Reduire les pertes sanguines et les besoins transfusionnels en chirurgie pediatrique]. Can J Anesth, June 1, 2006; 53(6_suppl): S59 - S67. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. A. Galel Therapeutic Techniques: Selection of Blood Components for Neonatal Transfusion NeoReviews, July 1, 2005; 6(7): e351 - e355. [Full Text] [PDF]
|
|
|
|
|
|
M. Nakagawa, M. Kubota, I. Endo, S. Inoue, and N. Seo Use of a K+-adsorption filter for the massive transfusion of irradiated red blood cells in a child Can J Anesth, June 1, 2004; 51(6): 639 - 640. [Full Text]
|
|
|
|
|
|
D. F. Szpisjak, D. S. Edgell, and B. Bissonnette Potassium as a Surrogate Marker of Debris in Cell-Salvaged Blood Anesth. Analg., July 1, 2000; 91(1): 40 - 43. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
