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Canadian Journal of Anesthesia, Vol 38, 102-104, Copyright © 1991 by Canadian Anesthesiologists' Society

ARTICLES

High-performance liquid chromatography as a diagnostic tool in prolonged neuromuscular blockade

D Mangar and PB Kane
SUNY Health Science Center, Department of Anaesthesiology, Syracuse 13210.

We report the use of high-performance liquid chromatography (HPLC) to identify the cause of prolonged neuromuscular blockade in a child who had received 2 mg.kg-1 of succinylcholine. Upon analysis by HPLC the syringe was found to contain succinylcholine (10 mg.ml-1) and also atracurium (5 mg.ml-1), so that a diagnosis was established. In situations where medication errors are suspected, we recommend saving syringe contents for analysis for confirmation of the agent.




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Copyright © 1991 by the Canadian Anesthesiologists' Society.