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Canadian Journal of Anesthesia, Vol 4, 27-36, Copyright © 1957 by Canadian Anesthesiologists' Society

Clinical Evaluation of Methyprylon (Noludar®)+ as a Preanaesthetic Sedative Hypnotic

ALLEN B. DOBKIN M.D.1, GORDON M. WYANT F.F.A.R.C.S.1, and FRANK DYCK 2

1 Department of Anaesthesia, University of Saskatchewan College of Medicine and University Hospital, Saskatoon. Supplies of Noludar® were made available through the courtesy of Dr. R. L. Wolfe, Medical Director, Hoffmann-LaRoche Ltd., Montreal, P. Q.
2 Student Research Assistant supported by a grant from the P. D. Stewart Bequest of the University of Saskatchewan

A controlled clinical evaluation of the psychological and physiological effects of Noludar was carried out in 171 patients in the preoperative state, employing this drug as a night sedative-hypnotic, and as preoperative medication, with or without the belladonna derivatives. Noludar was found to be a valuable agent for night sedation, but unsuitable for sedation in the immediate preoperative medication.






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Copyright © 1957 by the Canadian Anesthesiologists' Society.