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Canadian Journal of Anesthesia, Vol 4, 82-88, Copyright © 1957 by Canadian Anesthesiologists' Society

Evaluation of Plexonal as a Preoperative Hypnotic

GORDON M. WYANT F.F.A.R.C.S., ANTHONY P. MELGRAVE M.B., B.S.1, ALLEN B. DOBKIN M.D., and CHRISTOPHER J. J. KILDUFF M.B., B.CH.

1 Present address: Division of Anesthesia, University of Illinois Research & Educational Hospitals, Chicago 12, Illinois, U.S.A.

The effectiveness of Plexonal for preoperative night sedation has been tested in 250 patients, 100 of whom underwent a Double Blind Study.

The fallacy of relying on a straight study in the evaluation of these drugs has been demonstrated and the necessity of controlling results with a Double Blind Study has been emphasized. In the last resort it is the patient's subjective response to hypnotic medication which is of prime importance. In this respect Plexonal produced a mild but definite soporific effect.

Note:

Supplies of Plexonal were made available through the courtesy of Messrs. Sandoz Pharmaceuticals, Montreal, P.Q.

Department of Anaesthesia, University of Saskatchewan College of Medicine and University Hospital, Saskatoon, Saskatchewan.






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Copyright © 1957 by the Canadian Anesthesiologists' Society.