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Canadian Journal of Anesthesia, Vol 40, 227-246, Copyright © 1993 by Canadian Anesthesiologists' Society

ARTICLES

Potassium and anaesthesia

JE Tetzlaff, JF O'Hara Jr and MT Walsh
Department of General Anesthesia, Cleveland Clinic Foundation, Ohio 44195-5001.

Potassium is the principle intracellular ion, and its concentration and gradients greatly influence the electrical activity of excitable membranes. Because anaesthesia is so intimately involved with electrically active cells, potassium concentrations in surgical patients have received considerable attention in diagnostic and therapeutic applications. With the ongoing evolution in the indications for potassium, it is important to review the role of potassium in cellular activity, in storage and regulation, in diseases that alter potassium homeostasis, and in the therapeutic implications of perioperative alterations of potassium concentration. A rational approach to abnormal potassium values and the use of potassium in the operating room is sought, based on a physiological understanding of risks and benefits.




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Copyright © 1993 by the Canadian Anesthesiologists' Society.