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Canadian Journal of Anesthesia, Vol 40, 529-531, Copyright © 1993 by Canadian Anesthesiologists' Society

ARTICLES

Plasma cholinesterase deficiency in a neonate

CA Pasquariello and RE Schwartz
Department of Anesthesia and Critical Care, Temple University School of Medicine, Philadelphia, Pennsylvania.

We report a two-day-old infant who had a period of apnoea lasting six hours following the intravenous administration of succinylcholine (Sch). The results of her plasma cholinesterase level and dibucaine number indicate a congenital absence of plasma cholinesterase (PChE) enzyme, although both parents and siblings had normal cholinesterase levels and dibucaine numbers. This is believed to be the youngest reported case of prolonged apnoea after the administration of succinylcholine.




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Copyright © 1993 by the Canadian Anesthesiologists' Society.