| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Canadian Journal of Anesthesia, Vol 41, 1041-1046, Copyright © 1994 by Canadian Anesthesiologists' Society
ARTICLES |
BF Matta, AM Lam and TS Mayberg
Department of Anesthesiology, University of Washington School of Medicine, Harborview Medical Center, Seattle 98104.
Cerebral venous oxygen desaturation may occur when hyperventilation is employed during neurosurgical procedures. In this study, we examined the effect of arterial hyperoxia (PaO2 > 200 mmHg) on jugular bulb venous oxygen tension (PjvO2), saturation (SjvO2) and content (CjvO2) in 12 patients undergoing anaesthesia for neurosurgical procedures. Under stable anaesthetic conditions, the inspired oxygen fraction (FIO2) was varied to give four different levels of arterial oxygen tension (PaO2 100-200, 201-300, 301-400, and > 400 mmHg), at two levels of controlled hyperventilation (PaCO2(25) and 30 mmHg). In five patients, a transcranial Doppler probe was used to insonate the middle cerebral artery throughout the study period. Regression lines were constructed for each patient for the PjvO2, SjvO2 and the corresponding PaO2 for both levels of PaCO2 (all PjvO2-PaO2 and SjvO2-PaO2 regression lines r2 > 0.85, P < 0.0001). From these lines we calculated the PjvO2, SjvO2 and CjvO2 at PaO2 of 100, 250 and 400 mmHg, at each level of PaCO2 for each patient. At PaCO2 of 25 mmHg, hyperoxaemia increased PjvO2 (from 27.6 +/- 1.1 mmHg at PaO2 of 100 mmHg to 30.6 +/- 1.4 and 33.6 +/- 1.8 mmHg at PaO2 of 250 and 400 mmHg respectively) and SjvO2 (from 54 +/- 3% at PaO2 of 100 mmHg to 60 +/- 3 and 65 +/- 3% at PaO2 of 250 and 400 mmHg respectively, P < 0.05). Hyperoxaemia had a similar effect on SjvO2 and PjvO2 at a PaCO2 of 30 mmHg.(ABSTRACT TRUNCATED AT 250 WORDS)
This article has been cited by other articles:
 |
|
 |
|
  A. D. McLeod, F. Igielman, C. Elwell, M. Cope, and M. Smith Measuring Cerebral Oxygenation During Normobaric Hyperoxia: A Comparison of Tissue Microprobes, Near-Infrared Spectroscopy, and Jugular Venous Oximetry in Head Injury Anesth. Analg., September 1, 2003; 97(3): 851 - 856. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. R. Munoz, G. E. Nunez, J. E. de la Fuente, and M. G. Campos The Effect of Nitrous Oxide on Jugular Bulb Oxygen Saturation During Remifentanil Plus Target-Controlled Infusion Propofol or Sevoflurane in Patients with Brain Tumors Anesth. Analg., February 1, 2002; 94(2): 389 - 392. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Olive, M. Noguer, G. F. A. Jansen, M. B. Kedaria, J. A. Odoom, and B. H. van Praagh Global Cerebral Hypoperfusion and PaCO2 Response Anesth. Analg., April 1, 2000; 91(1): 246 - 246. [Full Text] [PDF]
|
|
|
|
|
|
R. M. Schell and D. J. Cole Cerebral Monitoring: Jugular Venous Oximetry Anesth. Analg., March 1, 2000; 90(3): 559 - 566. [Full Text] [PDF]
|
|
|
|
|
|
G. F. A. Jansen, B. H. van Praagh, M. B. Kedaria, and J. A. Odoom Jugular Bulb Oxygen Saturation During Propofol and Isoflurane/Nitrous Oxide Anesthesia in Patients Undergoing Brain Tumor Surgery Anesth. Analg., August 1, 1999; 89(2): 358 - 358. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
