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Canadian Journal of Anesthesia, Vol 43, 595-598, Copyright © 1996 by Canadian Anesthesiologists' Society

ARTICLES

Epidural morphine vs hydromorphone in post-caesarean section patients

SH Halpern, R Arellano, R Preston, J Carstoniu, G O'Leary, S Roger and A Sandler
Department of Anaesthesia, Women's College Hospital, Toronto, Ontario, Canada. halpern@ftn.net

PURPOSE: The purpose of this randomized controlled double blind study was to compare the efficacy of pain relief and the side effects of epidural hydromorphone and morphine in post-Caesarean patients. METHODS: In all patients, epidural anaesthesia was induced using carbonated lidocaine 2% with 1:200,000 epinephrine and 50 micrograms fentanyl, given in incremental doses. Patients in Group 1 (n = 24) received 0.6 mg hydromorphone and patients in Group 2 (n = 22) received 3 mg morphine after delivery of the infant. Pain, pruritus and nausea were measured using a visual analog scale (at times: baseline, on admission to the recovery room, 3, 6, 12, 18 and 24 hr postoperatively), by the number of requests for additional medications and by an overall satisfaction score. RESULTS: There was no difference between the groups in pain relief of in the incidence and severity of side effects. Pruritus was more pronounced within the first six hours in Group 1 and at 18 hr in Group 2. CONCLUSION: Hydromorphone provides no clinical benefit over epidural morphine for post operative analgesia following Caesarean section.


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 Canadian J. AnesthesiaHome page
R. K. Parker, N. R. Connelly, T. Lucas, U. Faheem, A. S. Rizvi, M. El-Mansouri, N. Thakkar, R. Kamasumadram, K. Dixon, S. M. Dunn, et al.
The addition of hydromorphone to epidural fentanyl does not affect analgesia in early labour: [L'addition d'hydromorphone a l'injection epidurale de fentanyl n'affecte pas l'analgesie au debut du travail]
Can J Anesth, June 1, 2002; 49(6): 600 - 604.
[Abstract] [Full Text] [PDF]


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Copyright © 1996 by the Canadian Anesthesiologists' Society.