| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Canadian Journal of Anesthesia, Vol 44, 1162-1166, Copyright © 1997 by Canadian Anesthesiologists' Society
ARTICLES |
T Shimizu, K Abe, K Kinouchi and I Yoshiya
Department of Anaesthesiology of Osaka University Medical School, Japan.
PURPOSE: To compare the effects of isoflurane and sevoflurane on arterial oxygenation and middle cerebral artery blood flow velocity during one lung ventilation. METHODS: This was a randomized, crossover study in 20 patients undergoing thoracotomy for oesophageal cancer and scheduled for long term one lung ventilation (OLV). They were randomized to one of two groups: group A, firstly isoflurane was administered followed by sevoflurane, and then isoflurane was resumed; group B, the order of the administration was reversed. Arterial blood gas samples were drawn at the start of OLV, 30 and 60 min after the initiation of OLV and the end of OLV (the change of volatile anesthetics was done 30 and 60 min after the start of OLV). Middle cerebral artery (MCA) was monitored continuously with the probe positioned over the temporal bone window. This probe transmitted 2 MHZ wave Doppler signals. Time-averaged MCA blood flow velocity was calculated from the signals. RESULTS: The PaO2 values decreased 30 min after the start of OLV (364.4 +/- 33.4 mmHg vs 179.0 +/- 19.5, and 338.7 +/- 24.8 mmHg vs 139.7-19.9 in groups A and B respectively), but there was no difference between the groups. Blood flow velocity of MCA did not change after the start of OLV (53.1 +/- 3.2, 55.9 +/- 3.0, 56.4 +/- 2.4, and 54.1 +/- 1.9 vs 50.8 +/- 2.1, 50.7 +/- 2.4, 53.7 +/- 1.5, 50.8 +/- 2.2 cm.sec-1 in groups A and B respectively): there was no difference between the groups. (P < 0.05). CONCLUSION: In clinical practice, the selection of either isoflurane and sevoflurane for OLV was of no difference in terms of the arterial blood oxygenation. With both agents MCA blood flow velocity was maintained during OLV.
This article has been cited by other articles:
 |
|
 |
|
  F. T. Lytle and D. R. Brown Appropriate Ventilatory Settings for Thoracic Surgery: Intraoperative and Postoperative Seminars in Cardiothoracic and Vascular Anesthesia, June 1, 2008; 12(2): 97 - 108. [Abstract] [PDF]
|
|
|
|
 |
|
 J. M. Alvarez, J. Tan, N. Kejriwal, K. Ghanim, M. A.J. Newman, A. Segal, G. Sterret, and M. K. Bulsara Idiopathic postpneumonectomy pulmonary edema: Hyperinflation of the remaining lung is a potential etiologic factor, but the condition can be averted by balanced pleural drainage J. Thorac. Cardiovasc. Surg., June 1, 2007; 133(6): 1439 - 1447. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. Pruszkowski, N. Dalibon, M. Moutafis, E. Jugan, J. D. Law-Koune, P. A. Laloe, and M. Fischler Effects of propofol vs sevoflurane on arterial oxygenation during one-lung ventilation Br. J. Anaesth., April 1, 2007; 98(4): 539 - 544. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ishikawa, K. Nakazawa, and K. Makita Progressive changes in arterial oxygenation during one-lung anaesthesia are related to the response to compression of the non-dependent lung Br. J. Anaesth., January 1, 2003; 90(1): 21 - 26. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
