CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Reimer, E. J.
Right arrow Articles by Merrick, P. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Reimer, E. J.
Right arrow Articles by Merrick, P. M.

Canadian Journal of Anesthesia, Vol 45, 1162-1167, Copyright © 1998 by Canadian Anesthesiologists' Society

ARTICLES

The effectiveness of clonidine as an analgesic in paediatric adenotonsillectomy

EJ Reimer, GS Dunn, CJ Montgomery, PM Sanderson, LD Scheepers and PM Merrick
Department of Anaesthesia, University of British Columbia, Vancouver, Canada. elreimer@interchange.ubc.ca

PURPOSE: To compare the analgesic effects of preoperative oral clonidine with intraoperative intravenous fentanyl in children undergoing tonsillectomy or adenotonsillectomy. METHODS: This randomized, controlled, double-blind study of 36 ASA I-II children, age 7-12 yr undergoing adenotonsillectomy was conducted at a tertiary care paediatric teaching hospital. Either 4 micrograms.kg-1 clonidine po was given 60-90 min preoperatively or 3 micrograms.kg-1 fentanyl i.v. was given intraoperatively. Postoperatively visual analog pain scores (VAS) were recorded at rest and on swallowing every 10 min for the first 30 min and then every 15 min for two hours. Morphine 0.05 mg.kg-1 i.v. was given for VAS > or = 5. If > 3 doses were required, 1.5 mg.kg-1 codeine po and 20 mg.kg-1 acetaminophen po were given. Sedation and anxiety scores were recorded preoperatively. Haemodynamic changes, blood loss, recovery scores, and the incidence of vomiting, hypotension, and airway obstruction were recorded. RESULTS: Children who received clonidine had a higher incidence of preoperative sedation (63%) than those receiving fentanyl (6%). Preinduction mean arterial pressure was lower in the clonidine group but required no intervention. VAS scores were similar throughout the observation period. There was no difference either in the number of morphine or codeine rescue doses administered or in the incidence of side effects. CONCLUSION: Oral clonidine is an effective analgesic and sedative for children undergoing tonsillectomy or adenotonsillectomy.


This article has been cited by other articles:


Home page
 Canadian J. AnesthesiaHome page
R. G. Cox
Anesthetic management of pediatric adenotonsillectomy
Can J Anesth, December 1, 2007; 54(12): 1021 - 1025.
[Full Text] [PDF]

Home page
 Arch Otolaryngol Head Neck SurgHome page
C. Giannoni, S. White, F. K. Enneking, and T. Morey
Ropivacaine With or Without Clonidine Improves Pediatric Tonsillectomy Pain
Arch Otolaryngol Head Neck Surg, October 1, 2001; 127(10): 1265 - 1270.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
M. E. McCann and Z. N. Kain
The Management of Preoperative Anxiety in Children: An Update
Anesth. Analg., July 1, 2001; 93(1): 98 - 105.
[Full Text] [PDF]

Home page
 Anesth. Analg.Home page
L. Fazi, E. C. Jantzen, J. B. Rose, C. D. Kurth, and M. F. Watcha
A Comparison of Oral Clonidine and Oral Midazolam as Preanesthetic Medications in the Pediatric Tonsillectomy Patient
Anesth. Analg., January 1, 2001; 92(1): 56 - 61.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1998 by the Canadian Anesthesiologists' Society.