CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS

This Article
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Guay, J.
Right arrow Articles by Hardy, J. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Guay, J.
Right arrow Articles by Hardy, J. F.

Canadian Journal of Anesthesia, Vol 45, 683-691, Copyright © 1998 by Canadian Anesthesiologists' Society


ARTICLES

[Polytrauma and hemostatic anomalies]

J Guay, Y Ozier, P de Moerloose, CM Samana, S Belisle and JF Hardy
Universite de Montreal, Departement d'Anesthesie-Reanimation, Hopital Maisonneuve-Rosemont, Quebec.

OBJECTIVE: Polytraumatized patients present with defects of haemostasis that manifest clinically either by haemorrhage and/or thrombosis. During the initial, as well as during the later phases of treatment, clinicians should take into account the most recent developments in the understanding, in the evaluation of the risk, and in the prevention of haemorrhagic and thrombotic complications. SOURCE: A group of experts, convened by the "Groupe d'interet en hemostase perioperatoire" (Perioperative Haemostasis Interest Group) during the Annual Meeting of the Association of Anaesthetists of Quebec, held a symposium to review and integrate recent developments on haemostatic complications associated with trauma. MAIN FINDINGS: The normal haemostatic balance is strongly compromised by trauma and shock. The percentage of patients with a coagulopathy and surgically uncontrollable haemorrhage varies between 18 and 40%. Abnormal coagulation after trauma is of multifactorial origin. Coagulopathy secondary to haemodilution is no longer considered the main cause of haemorrhage. Disseminated intravascular coagulation (DIC) is often manifest in the traumatic context. One out of every three polytraumatized patient will develop a deep vein thrombosis despite the preventive measures available at present. Clinical or laboratory detection of venous thrombosis either lacks sensitivity (physical examination or ultrasonography), or cannot be performed serially (phlebography). CONCLUSIONS: Prevention and treatment of disorders of haemostasis relies upon the rapid and effective treatment of shock associated with trauma. Prevention of thromboembolic complications is paramount, taking into account the evolving balance between the risk of haemorrhage and the risk of thrombosis.


This article has been cited by other articles:


Home page
Canadian J. AnesthesiaHome page
J.-F. Hardy, P. de Moerloose, C. M. Samama, and Members of the Groupe d'Interet en Hemostase Perio
Massive transfusion and coagulopathy: pathophysiology and implications for clinical management: [Transfusion massive et coagulopathie-: physiopathologie et implications cliniques].
Can J Anesth, June 1, 2006; 53(6_suppl): S40 - S58.
[Abstract] [Full Text] [PDF]


Home page
Canadian J. AnesthesiaHome page
J.-F. Hardy, P. de Moerloose, M. Samama, and members of the Groupe d'interet en Hemostase Perio
Massive transfusion and coagulopathy: pathophysiology and implications for clinical management: [Transfusion massive et coagulopathie : physiopathologie et implications cliniques]
Can J Anesth, April 1, 2004; 51(4): 293 - 310.
[Abstract] [Full Text] [PDF]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1998 by the Canadian Anesthesiologists' Society.