This Article Résumé de cet Article Full Text Full Text (PDF) Submit a scholarly reply Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ozaki, M. Articles by Shigematsu, A. Search for Related Content PubMed PubMed Citation Articles by Ozaki, M. Articles by Shigematsu, A.

Transdermal ketoprofen mitigates the severity of postoperative sore throat

[Le kétoprofène transdermique réduit le mal de gorge postopératoire]

From the Department of Anesthesiology, University of Occupational and Environmental Health, School of Medicine, Fukuoka, Japan.

Dr. Kouichiro Minami, Department of Anesthesiology, University of Occupational and Environmental Health, School of Medicine, 1-1, Iseigaoka, Yahatanishiku, Kitakyushu, Fukuoka, 807-8555, Japan. Phone: +81-93-691-7265; Fax: +81-93-601-2910; E-mail: kminami{at}med.uoeh-u.ac.jp

Purpose: To evaluate prospectively the incidence and severity of postoperative sore throat in 63 orotracheally intubated patients undergoing general anesthesia for various surgical procedures and to determine whether postoperative sore throat could be attenuated by treatment with the transdermal nonsteroidal anti-inflammatory drug ketoprofen applied on the anterior skin of the neck during operation.

Method: Patients were randomly assigned to have treatment with ketoprofen (ketoprofen group) or to have placebo tape treatment (control group). Postoperative analgesia was obtained by continuous epidural infusion of local anesthetics, and no narcotics were administered intraoperatively or postoperatively. All patients were interviewed postoperatively after 12–20 hr using a scoring scale questionnaire. Sore throat was scored as 0=no sore throat, 1=minimal, 2=mild, 3=moderate, 4=severe.

Results: In the control group, 16 of 32 patients had a sore throat. In the ketoprofen group, less patients (ten of 31 patients) had a sore throat (not significant). The severity of sore throat was alleviated significantly in the ketoprofen group (P <0.05).

Conclusion: This study suggests the pain caused by tracheal intubation is relieved by intraoperative topical use of transdermal ketoprofen.

This article has been cited by other articles:

				J. Ogata, K. Minami, T. Horishita, M. Shiraishi, T. Okamoto, T. Terada, and T. Sata Gargling with Sodium Azulene Sulfonate Reduces the Postoperative Sore Throat After Intubation of the Trachea Anesth. Analg., July 1, 2005; 101(1): 290 - 293. [Abstract] [Full Text] [PDF]