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An inventory of Canadian anesthesiology. Human research from 1995 through 1999

From the Departments of Paediatrics and Anaesthesia, Children's & Women's Health Centre of British Columbia, Vancouver, British Columbia, Canada.

Address correspondence to: Dr. Andrew Macnab, Critical Care Research Office, Room L317, Mail Box 80, Children's & Women's Health Centre of British Columbia, 4480 Oak Street, Vancouver, British Columbia, V6H 3V4, Canada. Phone: 604-875-3524; Fax: 604-263-5031; E-mail: regagnon{at}interchange.ubc.ca

Purpose: The year 2000 provides a symbolic opportunity to assess the past initiatives in anesthesia research. As in many other fields, medical research has benefited from utilizing computerized data bases to facilitate enumerating areas of interest. We have created a baseline survey of past research in the fields of anesthesia, anesthetics, analgesia, and analgesics to highlight Canadian studies.

Methods: The survey was undertaken using the Medical Literature Analysis and Retrieval System (MEDLARS) medical literature archive for the years 1995 through 1999. The principal categories and subcategories of MEDLARS' anesthesia classifications were counted for 70 countries contributing to the archive.

Results: Canadian contributions ranged from 141 (1992) to 185 (1999) and represented annually 3% of the world total in the anesthesia categories. The greatest number of studies (30–38%) were about adults aged 19 to 44 yr, and there were between 4% and 14% more studies of females than males. "Pharmacology" and "therapeutic use" were the most frequent topics, lidocaine, fentanyl, and propofol were the most studied anesthetics, and non-steroidal anti-inflammatories, opium, morphine, and fentanyl were the most studied analgesics. Among the types of studies, those classified as "quality of health care" occurred most frequently (16%). Canadian trends closely follow world trends.

Conclusion: The collected counts provide a comprehensive overview of research trends for the past five years.

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