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Gender and pain upon movement are associated with the requirements for postoperative patient-controlled iv analgesia: a prospective survey of 2,298 Chinese patients

[Les besoins d'analgésie iv auto-contrôlée sont liés au sexe du sujet et à la douleur au mouvement : une enquête auprès de 2 298 Chinois]

Yuan-Yi Chia, MD^*, Lok-Hi Chow, MD, Chun-Chieh Hung, MD^*, Kang Liu, MD^*, Luo-Ping Ger, RN MPH and Pei-Ning Wang, MD

^* From the Departments of Anesthesiology,
Medical Education and Research, Kaohsiung Veterans General Hospital National Yang-Ming University, School of Medicine, Kaohsiung; the Graduate Institute of Medical Science, National Defense Medical Center;
the Department of Anesthesiology, and
Neurological Institute, Taipei Veterans General Hospital The National Yang-Ming University School of Medicine Taipei Taiwan.

Dr. Yuan-Yi Chia, 386, Ta-Chung 1^st Rd, Kaohsiung 813, Department of Anesthesiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan. Phone: 886-7-346 8183; Fax: 886-7-346 8183; E-mail: yychia{at}isca.vghks.gov.tw

Purpose: To investigate prospectively the influence of patient characteristics upon, and the association of postoperative measurements with, the requirements for postoperative morphine and the assessment of resting pain and pain upon movement in Chinese patients.

Methods: From January 1998 to December1999, patients receiving patient-controlled iv morphine subsequent to general anesthesia and surgery at our institute (Kaohsiung Veterans General Hospital), were enrolled in the study. Demographic data (such as gender, age, weight, height and education level) and postoperative measurements, including pain scores at rest or during movement, sedation scores and morphine consumption, were recorded.

Results: In total 2,298 patients were recruited. Females consumed significantly less morphine via patient-controlled analgesia (PCA) in the first three postoperative days than was the case for males (P <0.05). Gender was the strongest predictor for postoperative morphine requirements. Postoperative pain upon movement was another effective predictor for morphine requirement (P <0.05). Age, body height, body weight, education and operation sites were not associated with morphine consumption.

Conclusion: Gender and postoperative pain upon movement are the major factors influencing morphine requirement for patient-controlled iv morphine analgesia during the first three postoperative days in Chinese patients.

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