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Canadian Journal of Anesthesia, Vol 5, 55-60, Copyright © 1958 by Canadian Anesthesiologists' Society

Epidural and Nerve Block Anaesthesia with Sympocaine

MAX S. SADOVE M.D.1, ANTHONY P. MELGRAVE M.B., B.S.1, and MYRON J. LEVIN M.D.1

1 College of Medicine, Division of Anesthesia, University of Illinois, Chicago 12, Illinois, and Department of Anesthesia, Hines Veterans Administration Hospital, Hines, Illinois

In all 413 patients were anaesthetized with Sympocaine 0.5 per cent without epinephrine. Most (175) of the blocks were caudal epidurals with a further 28 sacral and 41 thoraco-lumbar epidural anaesthetics. Possible toxic reactions were observed in 10 patients (2.5 per cent). Hypotension was noted in epidural type anaesthesia and was almost certainly related to the form of block. Temporary irritation occurred on intradermal injection in more than one-third of skin wheals, but this is considered to occur because the experimental solution contains 1:600 phenol. Onset is rapid, usually requiring 4–5 minutes, while duration of action varies between one and a half and two and a half hours. The most common doses for the several techniques are mentioned.

Sympocaine 0.5 per cent used in doses between 15 and 30.cc has been found to be reliable, to have moderate spreading ability, adequate effect and little evidence of toxic reaction.

Note:

Presented at the Annual Meeting, Canadian Anaesthetists' Society, Saskatoon, Saskatchewan, June 24–26, 1957.






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Copyright © 1958 by the Canadian Anesthesiologists' Society.