CJA
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Résumé de cet Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a scholarly reply
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Jabbour-Khoury, S. I.
Right arrow Articles by Baraka, A. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Jabbour-Khoury, S. I.
Right arrow Articles by Baraka, A. S.
Canadian Journal of Anesthesia 50:116-120 (2003)
© Canadian Anesthesiologists' Society, 2003
General Anesthesia

A combination of alfentanil-lidocaine-propofol provides better intubating conditions than fentanyl-lidocaine-propofol in the absence of muscle relaxants

[La combinaison d’alfentanil-lidocaïne-propofol fournit de meilleures conditions d’intubation que celle de fentanyl-lidocaïne-propofol en l’absence de myorelaxants]

Samar I. Jabbour-Khoury, MD, Aliya S. Dabbous, MD, Laudia B. Rizk, MD, Naji M. Abou Jalad, MD, Tonine E. Bartelmaos, MD, Mohamad F. El-Khatib, PhD and Anis S. Baraka, MD FRCA

From the Department of Anesthesiology, American University of Beirut Medical Center, Beirut, Lebanon.

Address correspondence to: Dr. Anis Baraka, Professor and Chairman, Department of Anesthesiology, American University of Beirut, P.O.Box 11-0236, Beirut, Lebanon. Phone: 961-1-350000, ext. 6380; Fax: 961-1-744464; E-mail: abaraka{at}aub.edu.lb

Purpose: To compare the ease of tracheal intubation without the use of muscle relaxants following an alfentanil-lidocaine-propofol sequence vs a fentanyl-lidocaine-propofol sequence.

Clinical features: In 80 ASA I and II adult patients undergoing elective laparoscopic surgery, we compared the intubating conditions following alfentanil 20 µg•kg–1, lidocaine 1.5 mg•kg–1, propofol 3 mg•kg–1 (Group I; n = 40) vs fentanyl 2 µg•kg–1, lidocaine 1.5 mg•kg–1, propofol 3 mg•kg–1 (Group II; n = 40). The intubating conditions were scored by jaw relaxation, vocal cord position and response to intubation, as well as by blood pressure and heart rate changes. The intubating conditions were good or excellent in 95% of patients in Group I vs 62.5% of patients in Group II (P < 0.05). Blood pressure decreased from a preinduction value of 86 ± 13 mmHg to 72 ± 28 mmHg and 74 ± 19 mmHg in Group I, and from 85 ± 12 mmHg to 78 ± 15 mmHg and 78 ± 12 mmHg in Group II, one and five minutes following intubation (P < 0.05). This drop in blood pressure was not different between the two groups.

Conclusion: An alfentanil-lidocaine-propofol sequence offers significantly better intubating conditions than a fentanyl-lidocaine-propofol sequence in healthy adult patients.




This article has been cited by other articles:


Home page
 Canadian J. AnesthesiaHome page
G. Kovacs, J. A. Law, J. Ross, J. Tallon, K. MacQuarrie, D. Petrie, S. Campbell, and C. Soder
Acute airway management in the emergency department by non-anesthesiologists: [L'assistance respiratoire immediate realisee a l'urgence par des non-anesthesiologistes]
Can J Anesth, February 1, 2004; 51(2): 174 - 180.
[Abstract] [Full Text] [PDF]

Home page
 Canadian J. AnesthesiaHome page
F. Donati
Tracheal intubation: unconsciousness, analgesia and muscle relaxation/Intubation tracheale: inconscience, analgesie et relachement musculaire
Can J Anesth, February 1, 2003; 50(2): 99 - 103.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2003 by the Canadian Anesthesiologists' Society.