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Canadian Journal of Anesthesia, Vol 6, 4-12, Copyright © 1959 by Canadian Anesthesiologists' Society

Regurgitation in Anaesthesia: A Report on Some Exploratory Work with Animals

J. G. ROBSON F.F.A.R.C.S. (ENG.)1 and P. WELT M.D.1

1 Wellcome Research Department of Anaesthesia, McGill University, Montreal

The results of some experimental work with the cardiac sphincter mechanism of cats and dogs are reported. Several methods of investigation were employed. (a) The peristaltic reflex of the lower end of the oesophagus was elicited by steady or rhythmic inflation of a balloon in the area. The tone was also determined. (b) The compliance of the cardiac sphincter to perfusion from the stomach was examined, with and without gastric dilatation. The results indicated that gastric dilatation is an important factor in regurgitation.

The acidity or alkalinity of the gastrict contents modified the response of the sphincter. Atropine and ether in the cat and ether and succinylcholine in the dog inhibited the peristaltic reflex and reduced tone.






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Copyright © 1959 by the Canadian Anesthesiologists' Society.