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Canadian Journal of Anesthesia, Vol 8, 210-215, Copyright © 1961 by Canadian Anesthesiologists' Society

A Study of Methoxyflurane Anaesthesia

R. A. MILLAR M.D. (EDIN.), M.SC., F.F.A.R.C.S.1 and M. E. MORRIS M.D., C.M.2

1 Department of Anaesthesia, Montreal Neurological Institute & McGill University, Montreal, Quebec
2 In receipt of a Sir Edward W. Beatty Memorial Scholarship

Methoxyflurane anaesthesia in dogs produced respiratory depression, a gradual moderate decline in blood pressure with minimal changes in heart rate, and no significant effect on blood glucose or plasma adrenaline and noradrenaline levels. Hypercarbia induced an immediate hypotensive response and caused significant increases in both catecholamines; haemorrhage was followed by significant increases in plasma adrenaline. Blood glucose increased as a result of hypercarbia and haemorrhage during methoxyflurane anaesthesia.






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Copyright © 1961 by the Canadian Anesthesiologists' Society.