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Canadian Journal of Anesthesia, Vol 8, 387-393, Copyright © 1961 by Canadian Anesthesiologists' Society

Circulatory Response to Tilt with Some Anti-Emetic and Sedative Drugs

ALLEN B. DOBKIN M.D.1 and V. GUY CRISWICK 2

1 Present address: Department of Anesthesiology, University Hospital, Upstate Medical Center, Syracuse, New York
2 Medical Student Research Assistant

The circulatory response in the supine position and in the 60° head-up tilt was compared in eight healthy male subjects with a therapeutic dose of trimethobenzamide, trimeprazine, diphenhydramine; dimenhydrinate, cyclizine, methaminodiazepoxide, and haloperidol. None of these drugs caused a significant alteration in the pulse rate or blood pressure, even in the head-up tilt position. Aside from drowsiness, none of the drugs except haloperidol caused undesirable side-effects.

Note:

Department of Anaesthesia, University of Saskatchewan College of Medicine and University Hospital, Saskatoon, Sask.






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Copyright © 1961 by the Canadian Anesthesiologists' Society.