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Canadian Journal of Anesthesia, Vol 9, 263-269, Copyright © 1962 by Canadian Anesthesiologists' Society

Electrocardiographic Changes Following Repeated Injections of Decamethonium and Subsequent Injections of Succinylcholine

R. T. WILLIAMS M.R.C.S., L.R.C.P.1 and E. A. GAIN M.D.1

1 Department of Anaesthesia, University of Alberta Hospital, Edmonton, Alberta

Seventeen patients were given repeated injections of decamethonium up to a maximum of 10 mg. Fifteen patients showed E.C.G. changes or a significant bradycardia after either the second or the third injection. Sixteen patients were given succinylcholine following the decamethonium, five of whom developed a significant bradycardia. The similarity in chemical structure of these two muscle relaxants to acetylcholine is mentioned.






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Copyright © 1962 by the Canadian Anesthesiologists' Society.