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Right arrow Cardiothoracic Anesthesia, Respiration and Airway
Canadian Journal of Anesthesia 47:215-219 (2000)
© Canadian Anesthesiologists' Society, 2000
Reports of Investigation

Advancement of the mandible facilitates nasal breathing in human subjects sedated with midazolam

Yasuko Kawauchi, MD*, Tsutomu Oshima, MD PhD{dagger}, Satomi Suzuki, MD*, Yuhji Saitoh, MD PhD* and Hidenori Toyooka, MD PhD{ddagger}

* From the Departments of Anesthesiology, School of Medicine, Tokyo Medical and Dental University, Tokyo,
{dagger} Gifu University School of Medicine, Gifu and the
{ddagger} Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan.

Address correspondence to: Tsutomu Oshima MD, Department of Anesthesiology and Critical Care Medicine, Gifu University School of Medicine, 40 Tsukasamachi, Gifu-City, Gifu 500-8705, Japan. Phone: 81-58-267-2295; Fax: 81-58-267-2961; E-mail: oshimat{at}cc.gifu-u.ac.jp

Objectif : Déterminer l'effet de la mobilisation antérieure de la mandibule (MM) sur la respiration nasale spontanée chez des volontaires sains qui reçoivent du midazolam par voie intraveineuse.

Méthode : Chez quatre sujets qui présentaient une respiration nasale pendant la sédation avec du midazolam (dose intraveineuse : 0,09 ± 0,02 mg•kg-1, moyenne ± écart type), nous avons mesuré la fréquence respiratoire (FR), la vitesse maximale de l'écoulement d'air inspiratoire nasal (maxIn), la vitesse maximale de l'écoulement d'air expiratoire nasal (maxEn), le coefficient de durée (Ti/Ttot) et la résistance nasale (Rn) avant et après la MM. On obtient la résistance nasale en divisant la pression différentielle masque nasal-oropharynx par la vitesse d'écoulement de l'air lors de l'inspiration nasale maximale.

Résultats : La FR, la maxIn, et la maxEn ont augmenté après la MM (P < 0,001, respectivement). Par contre, Ti/Ttot a diminué après la MM (P < 0,001). En conséquence, la MM a réduit la Rn de 30,4 ± 40,8 à 5,0 ± 5,6 (cmH2O•l–1•s-1) (moyenne ± écart type) (P < 0,001). Chez les quatre sujets, aucun écoulement de l'air par voie orale n'a été noté avant et après la MM.

Conclusion : La mobilisation antérieure de la mandibule réduit la résistance nasale et facilite ainsi la respiration nasale spontanée chez des humains normaux qui reçoivent du midazolam.




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[Abstract]

This Article
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