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Canadian Journal of Anesthesia 48:1011-1014 (2001)
© Canadian Anesthesiologists' Society, 2001

Cardiothoracic Anesthesia, Respiration and Airway

Hepatosplanchnic oxygenation is better preserved during mild hypothermic than during normothermic cardiopulmonary bypass

[L'oxygénation hépatosplanchnique est mieux préservée pendant la circulation extracorporelle sous légère hypothermie que sous normothermie]

Nobuhiro Okano, MD*, Haruhiko Hiraoka, MD*, Ryoichi Owada, MD*, Nao Fujita, MD*, Yuji Kadoi, MD{dagger}, Shigeru Saito, MD{dagger}, Fumio Goto, MD{dagger} and Toshihiro Morita, MD*

* From the Department of Anesthesiology, Saitama Cardiovascular and Pulmonary Center, Saitama; and
{dagger} the Department of Anesthesiology and Reanimatology, Gunma University, School of Medicine, Gunma, Japan.

Dr. Nobuhiro Okano, Department of Anesthesiology, Saitama Cardiovascular and Pulmonary Center, 1696 Itai Konan-machi Osato-gun, Saitama 360-0105, Japan. Phone: 81-48-536-9900; Fax: 81-48-536-9920; E-mail: richard{at}ka2.so-net.ne.jp

Objectif :Évaluer et comparer les effets de la circulation extracorporelle (CEC), sous normothermie ou hypothermie légère, sur l'oxygénation hépatosplanchnique.

Méthode : Nous avons étudié 14 patients devant subir un pontage aortocoronarien avec CEC sous normothermie (> 35 °C; groupe I, n = 7) ou hypothermie légère (32 °C; groupe II, n = 7). Après l'induction de l'anesthésie, un cathéter a été inséré dans la veine hépatique droite pour permettre de vérifier la saturation en oxygène du sang veineux hépatique (SO2vh) et le débit sanguin hépatosplanchnique par une perfusion constante utilisant le vert d'indocyanine.

Résultats : La SO2vh a diminué de sa valeur de base dans les deux groupes et a été significativement plus basse à 10 minutes et à 60 min après le début de la CEC dans le groupe I (39,5 ± 16,2 % et 40,1 ± 9,8 %, respectivement) que dans le groupe II (61,1 ± 16,2 % et 61,0 ± 17,9 %, respectivement; P < 0,05). Le taux d'extraction d'oxygène hépatosplanchnique pendant la CEC a été significativement plus élevé dans le groupe I que dans le groupe II (44,0 ± 7,2 % vs 28,7 ± 13,1 %; P < 0,05).

Conclusion : L'oxygénation hépatosplanchnique a été mieux préservée pendant la CEC sous hypothermie légère que sous normothermie.




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This Article
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