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Canadian Journal of Anesthesia 53:961 (2006)
© Canadian Anesthesiologists' Society, 2006

Correspondence

REPLY

Tiberiu Ezri, MD*, Peter Szmuk, MD{dagger} and Michael Muggia-Sullam, MD*

* Wolfson Medical Center, Holon, Israel, University of Texas Medical School and
{dagger} Children’s Medical Center at Dallas, Dallas, USA

We would like to thank Michael Caswell, PhD, for his important observations regarding the dose and contraindications to the use of sodium phosphate salts for bowel preparation prior to surgery.

First, as we stated in our manuscript, the drug was not used in cases where it was contraindicated.1 Secondly, although we did use 90 mL of solution, we prescribed the medication in two doses, separated by an eight-hour interval. While the time interval between the administration of doses varies amongst studies, a 90 mL volume, administered in two separate doses is recommended in the drug leaflet (Soffodex by Dexxon Ltd, Or-Akiva, Hadera, Israel) and several recently published studies.2–4

References

1 Ezri T, Lerner E, Muggia-Sullam M, et al. Phosphate salt bowel preparation regimens alter perioperative acid-base and electrolyte balance. Can J Anesth 2006; 53: 153–8.[Abstract/Free Full Text]

2 Muzii L, Bellati F, Zullo MA, Manci N, Angioli R, Panici PB. Mechanical bowel preparation before gynecologic laparoscopy: a randomized, single-blind, controlled trial. Fertil Steril 2006; 85: 689–93.[Medline]

3 Delegge M, Kaplan R. Efficacy of bowel preparation with the use of a prepackaged, low fibre diet with a low sodium, magnesium citrate cathartic vs. a clear liquid diet with a standard sodium phosphate cathartic. Aliment Pharmacol Ther 2005; 21: 1491–5.[Medline]

4 Huppertz-Hauss G, Bretthauer M, Sauar J, et al. Polyethylene glycol versus sodium phosphate in bowel cleansing for colonoscopy: a randomized trial. 2005; 37: 537–41.


Related articles in CJA:

Phosphate salt bowel preparation regimens alter perioperative acid-base and electrolyte balance
Michael Caswell
CJA 2006 53: 961. [Full Text]  




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