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Tuesday June 26; 0800 - 1000 |
1 University of Toronto, University Health Network, Toronto, ON, Canada
2 University of Toronto, University Health Network
3 University of Toronto, University Health Network
4 University of Toronto, University Health Network
5 University of Toronto, University Health Network
6 University of Toronto, University Health Network
Abstract
Introduction: Obstructive sleep apnea (OSA) affects millions of middle-aged men and women. At least 80% of moderate to severe OSA patients are undiagnosed before surgery and thus remain untreated perioperatively(1). In the preadmission clinics, a concise screening tool for OSA will be a great help for anesthesiologists. Berlin questionnaire (BQ) was developed for the screening of OSA in a primary care setting. We developed the OSA questionnaire (OSAQ) a new concise screening tool for OSA. The objective of this study was to validate the BQ and OSA questionnaire for the screening of OSA in surgical patients by comparing these questionnaires to polysomnographic (PSG) study, the gold standard in diagnosing OSA.
Methods: Hospital ethics approval and informed consent was obtained. All eligible preadmission clinic patients, age≥18 years, ASA I-IV, were screened for OSA using BQ and OSA questionnaire. BQ consists of 9 item regarding snoring behavior, wake-time sleepiness or fatigue and the presence of obesity or hypertension. OSA questionnaire contains 4 questions: "Do you snore loudly (louder than talking or loud enough to be heard through closed doors)?", "Do you often feel tired, fatigued or sleepy during daytime?", "Do you have or are you being treated for high blood pressure?" and "Has anyone noticed you stop breathing during your sleep?" Based on response to questions, patients were classified as high risk if they responded yes to two or more questions to OSAQ. All patients screened were invited for PSG. PSG scorers were blinded to the results of the 2 questionnaires. McNemars test was used to analyse the agreement between the 2 methods and PSG data.
Results: 2426 patients were screened with BQ and OSA questionnaire. BQ identified 23.4% (567/2426) whereas OSA questionnaire identified 22.3% (541/2426) as being at high risk for OSA. 2003 patients were invited for PSG, 223 patients gave informed consent and 1780 patients refused. 94 patients completed PSG. Mean age 57 ± 13 years, M:F - 56%:44% and ASA I:7.4%, II:50%, III:40.4%, IV:2.2%. With PSG, 39% (55/141) of patients were diagnosed to have moderate-severe OSA, AHI>15/hr (table
). Sensitivity, specificity, positive predictive value, negative predictive value of BQ was 0.69, 0.45, 0.47 and 0.68 and of OSA questionnaire 0.71, 0.49, 0.50 and 0.71. Using McNemars test, both questionnaires agreed with AHI in diagnosing OSA patients (p<0.05).
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